Oslin DW, Streim JE, Katz IR, Smith BD, DiFilippo SD, Ten Have TR, Cooper T (2000) Heuristic
comparison of sertraline with nortriptiline for the treatment of depression in frail elderly
patients. Am J Geriatr Psychiatry 8(2):141–149
Patel T, Slonim K, Lee L (2017) Use of potentially inappropriate medications among ambulatory
home-dwelling elderly patients with dementia: a review of the literature. Can Pharm J 150(3):
169–183
Payne GW, Bearden SE (2006) The microcirculation of skeletal muscle in aging. Microcirculation
13(4):275–277
Pei Q, Wang Y, Hu Z-Y, Liu S-K, Tan H-Y, Guo C-X, Zhang R-R, Xiang Y-X, Huang J, Yuan H,
Yang G-P (2014) Evaluation of the highly variable agomelatine pharmacokinetics in Chinese
healthy subjects to support bioequivalence study. PLoS ONE 9(10):e109300. https://doi.org/10.
1371/journal.pone.0109300
Poggesi I, Pellizzoni C, Fleishacker JC (2000) Pharmacokinetics of reboxetine in elderly patients
with depressive disorders. Int J Clin Pharmacol Ther 38(5):254–259
Pottel H, Delanaye P, Weekers L, Selistre L, Goffin K, Gheysens O, Dubourg L (2017)
Age-dependent reference intervals for estimated and measured glomerular filtration rate. Clin
Kidney J 10(4):545–551
Rao N (2007) The pharmacokinetics of escitalopram. Clin Pharmacokinet 46(4):281–290
Rayner CK, Horowitz M (2013) Physiology of the ageing gut. Curr Opin Clin Nutr Metab Care
16(1):33–38
Rémond D, Shahar DR, Gille D, Pinto P, Kachal J, Peyron MA, Dos Santos CN, Walther B,
Bordoni A, Dupont D, Tomas-Cobos L, Vergeres G (2015) Understanding the gastrointestinal
tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget 6(16):
13858–13898
Rodriguez-Castro KI, Franseschi M, Noto A, Miraglia C, Nuovenne A, Leandro G, Meschi T, de'
Angelis GL, Di Mario F (2018) Clinical manifestation of chronic atrophic gastritis. Acta
Biomed 89:88–92
Ronfeld RA, Tremaine LM, Wilner KD (1997) Pharmacokinetics of sertraline and its N-demethyl
metabolite in elderly and young male and female volunteers. Clin Pharmacokinet 32(Suppl 1):
22–30
Rubin EH, Biggs JT, Preskorn SH (1985) Nortriptyline pharmacokinetics and plasma levels:
implications for clinical practice. J Clin Psychiatry 46(10):418–424
Russell RM (2001) Factors in aging that effect the bioavailability of nutrients. J Nutr 131-
(4 Suppl):1359S–1361S
Saiz-Rodriguez M, Belmonte C, Román M, Ochoa D, Lopez-Rodriguez R, Cabaleiro T, Abad-
Santos F (2018) Effect of polymorphism on the pharmacokinetics, pharmacodymanics and
safety of sertraline in healthy volunteers. Basic Clin Pharmacol Toxicol 122(5):501–511
Saiz-Ruiz J, Montes JM, Alvarez E, Cervera S, Giner J, Guerrero J, Seva A, Dourdi F, Lopez-Ibor JJ
(1998) Taneptine therapy for depression in the elderly. Prog Neuro-Psychopharmacol Biol
Psychiatry 22(2):319–329
Salazar N, Valdes-Varela L, Gonzalez S, Gueimonde M, de Los Reyes-Gavilan CG (2017)
Nutrition and the gut microbiome in the elderly. Gut Microbes 8(2):82–97
Sampson MR (2013) Pharmacokinetics of antimicrobials in obese children. GaBI J 2(2):76–81
Samuels BA, Nautiyal KM, Kruegel AC, Levinstein MR, Magalong VM, Gassawaay MM, Grinell
SG, Han J, Ansonoff MA, Pintar JE, Javitch JA, Sames D, Hen R (2017) The behavioral effects
of the antidepressant tianeptine require the mu-opioid receptor. Neuropsychopharmacology 42:
2052–2063
Saraghi M, Golden L, Hersh EV (2018) Anesthetic considerations for patients on antidepressant
therapy—part II. Anesth Prog 65:60–65
Schmucker DL (2001) Liver function and phase I drug metabolism in the elderly: a paradox. Drugs
Aging 18(11):837–851
Schulz P, Turner-Tamiyasu K, Smith G, Giacomini KM, Blaschke TF (1983) Amitriptyline
disposition in young and elderly normal men. Clin Pharmacol Ther 33(3):360–366
270
M. Bhaskar et al.